X-Rhodamine maleimide ，ROX 马来酰亚胺，实验室常用的荧光染料

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文章关键词：X-Rhodamine maleimide ，X-Rhodamine mal，ROX-maleimide，ROX 马来酰亚胺

一、基本信息

【产品简介】：ROX, also known as Rhodamine 101, is a product whose active group is maleimide. Maleimide is a widely used group in biomarker reactions, which has unique chemical properties and can undergo affinity addition reactions with thiol groups (- SH). The thioester structure generated by this reaction is very stable, thus achieving the purpose of labeling. The chemical structure of maleimide enables it to react with thiol groups, forming stable thiol ether bonds. The formation of this bond is a crucial step in biomarker reactions, as it can permanently connect two molecules together. In biomarker reactions, maleimide is often used as a labeling agent, which can react with molecules containing thiol groups to generate stable thiol ether structures. This reaction process is reversible and can be achieved by removing or reconnecting labels under appropriate conditions. The affinity addition reaction of maleimide has high selectivity and only reacts with thiol groups. This selective reaction characteristic makes maleimide an ideal functional group in biomarker reactions. In biomarker reactions, maleimide can react with molecules containing thiol groups to generate stable thiol ether structures, thereby achieving labeling.

【中文名】：ROX 马来酰亚胺

【英文名】：X-Rhodamine maleimide ，X-Rhodamine mal，ROX-maleimide

【化学式】：C39H36N4O6

【分子量】：656.73

【结构式】：